Phenylephrine is also known as: AH-Chew D, Biorphen, Congest Aid II, Contac-D, Despec-SF, Dimetapp Toddler's Drops Decongestant, Gilchew IR, Help I Have A Stuffy Nose, Little Colds Decongestant, Lusonal, Nasal Decongestant PE, Nasop, Nasop12, Neo-Synephrine, PediaCare Children's Decongestant, Phenyl-T, Ricobid-D, Sudafed PE Children's Nasal Decongestant, Sudafed PE Congestion, Sudogest PE, Suphedrine PE, Triaminic Thin Strips Cold with Stuffy Nose, Vazculep. People who are pregnant or breastfeeding should speak with a doctor before taking nasal decongestants. There is a problem with There are no adequate scientific studies to prove the safe use of the decongestant medication phenylephrine when pregnant. First-trimester exposure may have harmful fetal outcomes, but the intranasal application has a lower risk. Too much phenylephrine may worsen congestion, increase blood pressure, or decrease heart rate, among other side effects. Sinus pressure can be a symptom of infection or allergies. These work by constricting (narrowing) blood vessels. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Ectopic pregnancy: Epidemiology, risk factors, and anatomic sites. All rights reserved. Serious side effects have been reported with phenylephrine including the following: Phenylephrine can cause blurred vision. Ask your doctor or pharmacist for more information. Were proud to be a team of writers who are truly passionate about all things health.Coming together from all parts of the world, we share a common goal of helping serve many with our comprehensive research and clear writing style. Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during 2nd and 3rd trimesters, but I couldn't help but worry myself. And phenylpropanolamine (Acutrim) was also linked to an eight-fold risk of defects of the ear and a three-fold increase in stomach defects. You should consult with a medical professional if you have any questions about your health. Ask your doctor or pharmacist for more information. To prevent the condition, doctors and pharmacists recommend avoiding the use of topical nasal decongestants for no more than a few days in a row. All quotes delayed a minimum of 15 minutes. In addition, I believe you must avoid random over-the-counter medicines for your safety and that of your unborn child. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. All rights reserved. The following chart displays important facts about pseudoephedrine and phenylephrine, including their uses, medication forms, and strengths in milligrams (mg). accidentally took phenylephrine - i iluvsparkles Posted 12/10/09 Ok, so I have read here on BBC that phenylephrine is generally ok in small ammounts during Maternal use of oral contraceptives and risk of birth defects in Denmark: Prospective, nationwide cohort study. Taking phenylephrine chronically could cause growth restriction (small size related to decreased blood flow to the baby). Phenylephrine should be given to a pregnant woman only if clearly needed. His team worked with a large collection of data on babies born with birth defects between 1993 and 2010. Every fetus depends on the same blood flow for every essential function to form ultimately. TELL US: Did your OB warn you about taking decongestants while pregnant? To tackle cold-like symptoms, you can increase fluid intake, increase resting time, take warm baths and even use humidifiers. Also, avoid drinking grapefruit juice while taking this drug. Can i take hydrochloride phenylephrine nose drops while pregnant? Normally, the first thing you'd do is reach for the nearest decongestant. The dose may be repeated every 3 to 5 minutes up to a maximum of 3 drops in each eye. This medication comes in solution form and is injected into a vein by a healthcare professional during surgical procedures. All were associations that had been suggested by earlier studies. To provide you with the most relevant and helpful information, and understand which Category c means you can take it, but you and your doctor need to carefully weigh the benefits vs. Even the eight-fold increase in risk indicated by the study results, while it sounds large, would translate to a 2.7 in 1,000 chance the baby would have the defect, he said. Major Pharmaceuticals Inc (2019): United States National Library of Medicine "Toxnet. Acetaminophen: Routinely used during all stages of pregnancy, it appears safe for short-term use. Sinus Congestion and Pain Daytime Cool Ice, Vicks QlearQuil Daytime Sinus & Congestion, acetaminophen and phenylephrine Consumer Information, Benadryl Dosage Charts (Infants & Children), Cerner Multum, Inc. "UK Summary of Product Characteristics." AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Taking birth control pills during early pregnancy doesn't appear to increase the risk of birth defects. Phenylephrine is a decongestant.. Acetaminophen, diphenhydramine, and phenylephrine is a combination medicine used to treat cold and flu symptoms such as runny or stuffy nose, sneezing, cough, sore throat, headache, fever, and body aches.. Use should be avoided.Excreted into human milk: Yes (acetaminophen) /Data not available (phenylephrine)Excreted into animal milk: Data not available (phenylephrine)Comments:-The amount of acetaminophen in breast milk is much less than typical infant doses.-One study calculated that infants receive about 0.14% of the parental absolute acetaminophen dose, or about 2% of the maternal weight-adjusted dosage.-Phenylephrine oral bioavailability is about 40%, making it unlikely an infant would receive large doses from breast milk.-Phenylephrine may decrease milk production. Animal studies have not been conducted. VAZCULEP- phenylephrine hydrochloride injection, DailyMed: Current Medication Information; U.S. National Library of Medicine. If you took a decongestant in the first trimester your child would have about a 2.7 in 1,000 chance of having a defect. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Pregnant people may also be prone to infections which may necessitate the prescription of some drugs. Avoid Some of them may require surgery, but not all are life-threatening.. Phenylephrine is not safe for consumption by pregnant women, especially in the first trimester of their pregnancy. It might feel convenient to take a decongestant in case of a cold or allergy, but it could have adverse effects on your babys development. Doctors typically provide answers within 24 hours. Take this medication exactly as prescribed by your doctor. dizziness. Major birth defects of any kind affect about two to three percent of liveborn infants, so they are rare, study author Dr. Allen Mitchell said. Repeated or long-term use of phenylephrine and other nasal decongestants can also lead to a condition called rebound congestion. Please contact the moderators of this subreddit if you have any questions or concerns. TGA. The combination of fenfluramine and phentermine had been widely used to promote weight loss, and many women were inadvertently exposed during the first trimester of pregnancy. I tend not Can i take medications containing phenylephrine while pregnant? Nighttime pills typically contain either phenylephrine or pseudoephedrine in addition to an antihistamine, a substance that causes drowsiness in most people. Tell your doctor if you are breastfeeding or plan to breastfeed. I think you can take pseudoephedrine which is actually sudafed before all the meth stuff. I know we can take Benedryl and the active ingredient is actually whats in Tylenol PM without the antecitaminophen. Some of the side effects can be common and easy to deal with, such as tiredness, droopiness, and partial insomnia. By posting, you are agreeing to our Terms of Use and understand that all information is taken at your own risk. Pregnancy categories A, B, C, D, and X are being phased out. Store phenylephrine eye drops at room temperature. The use of any information on this site is solely at your own risk. The FDA also controls how much pseudoephedrine a person can purchase in a given month. Based A woman who uses decongestant medications like pseudoephedrine while in the first trimester of pregnancy Sinus congestion occurs when fluid becomes trapped in the sinuses. Immediate release tablets: 30 mg or 60 mg. Mapap Sinus Congestion and Pain (acetaminophen-phenylephrine)." Such side effects may include vomiting, temperature increase, and even coma, all of which you should seek emergency medical attention. 12 The American College of Obstetricians and Gynecologists The recommended dose of phenylephrine for the treatment of low blood pressure due to anesthesia during surgery is 40 to 100 mcg every 1 to 2 minutes as a bolus intravenous injection or 10 to 35 mcg/min as an intravenous infusion. We comply with the HONcode standard for trustworthy health information. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. You can find out more and change our default settings with Cookies Settings. This medication is considered relatively safe in pregnancy (category c). As a result, they may lose a lot of blood during delivery; whether expected delivery or caesarian, they have to take iron supplements to boost their blood levels and avoid future emergencies. Extended release: Take 120 mg every 12 hours or 240 mg every 24 hours. This includes those taking existing medications, individuals with underlying health conditions, and those who are pregnant or breastfeeding. This drug crosses the placenta. You may opt-out of email communications at any time by clicking on Certain people need to speak with a doctor before they consider taking decongestants. They carry several risks, depending on the stage of pregnancy: First trimester. Phenylephrine belongs to a group of drugs called sympathomimetic agents. The common side effects may be less manifested and even easily tolerable over time as your body acclimates to Sudafed PE. If an individual does develop rebound congestion overusing a topical nasal decongestant, they must stop using the medication immediately. First-trimester use of phenylephrine, which is found in Sudafed among other products, was tied to an eight-fold higher risk of a heart defect called endocardial cushion defect. Mitchell believes theres enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each womans need for the drugs on a case-by-case basis. Phenylephrine may cause difficulty in falling asleep or staying asleep in some people ( 6 ). Avoiding Drug Drug Interactions: Here's How, Having Surgery? Top answers from doctors based on your search: Created for people with ongoing healthcare needs but benefits everyone. a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), oxytocic drugs such as oxytocin (Pitocin), tricyclic antidepressants such as trimipramine (Surmontil), amitriptyline (Elavil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil), and clomipramine (Anafranil), angiotensin-converting enzyme (ACE) blockers such as benazepril (Lotensin, Lotensin HCT), captopril (Capoten, Capozide), enalapril (Vasotec, Vaseretic), fosinopril (Monopril, Monopril HCT), lisinopril (Prinivil, Prinzide, Zestril, Zestoretic), moexipril (Univasc, Uniretic), quinapril (Accupril, Accuretic, Quinaretic), ramipril (Altace), and trandolapril (Mavik, Tarka), angiotensin receptor II blockers such as azilsartan (Edarbi), candesartan (, norepinephrine transporter inhibitors, such as atomoxetine (Strattera), ergot alkaloids, such as methylergonovine maleate, -adrenergic antagonists such as doxazosin (Cardura) and prazosin (Minipress), phosphodiesterase type 5 inhibitors such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Cialis), vardenafil (Levitra), certain medications for high blood pressure such as carvedilol (Coreg) and labetalol, calcium channel blockers, such as nifedipine (Adalat, Nifedical, Procardia), amlodipine (Norvasc), verapamil (Calan, Isoptin, Covera, Verelan), and diltiazem (Cardizem). -Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and Medically reviewed by Drugs.com. The baby didn't seem to even be effected from it at all and was moving around normally in there. Your doctor and you will decide if the benefits outweigh the risk of using phenylephrine. That may reduce the amount of blood flowing into the uterus. Can I take methylprednisolone with phenylephrine, Can i take phenylephrine with diphenhydramine. 2023 The Heart & Brain. In some states, the drug is only available to people over the age of 18 years. For the bot: 25F, 55, no other meds, non smoker, no PMH. Enter multiple addresses on separate lines or separate them with commas. We avoid using tertiary references. When ingested, phenylephrine may not only narrow the blood vessels inside the nasal cavity but can also do the same to the blood vessels inside the uterine wall. http://www.tga.gov.au/docs/html/medpreg.htm" (2010): "Product Information. If you are a Mayo Clinic patient, this could I am currently taking a sudafed (phenelephrine) about every 6 hours to help relieve this crazy snius/cold whatever. The risk of drug interaction may be primarily why all pregnant mothers drugs should be by prescription. You could take some Benedryl to help you sleep too. Non smoker, no other meds, non smoker, no other meds, non smoker no. Dailymed: Current medication information ; U.S. National Library of Medicine `` Toxnet antihistamine, a that... Sinus pressure can be a symptom of infection or allergies ): `` Product information standard! By posting, you can take Benedryl and the active ingredient is actually whats in Tylenol PM without antecitaminophen! The uterus our Terms of use and understand that all information is taken at your own risk,... Pills typically contain either phenylephrine or pseudoephedrine in addition to an eight-fold risk defects. In solution form and is injected into a vein by a healthcare professional during surgical procedures ( )!, the first trimester your child would have about a 2.7 in 1,000 chance of having a defect out! Or long-term use of phenylephrine and other nasal decongestants can also lead to a group of drugs called agents., risk factors, and partial insomnia check out these best-sellers and special offers books. Time as your body acclimates to sudafed PE an eight-fold risk of drug may! The ear and a three-fold increase in stomach defects your agreement to the baby ). phenylpropanolamine! Our Terms of use and understand that all information is taken at your own risk and.! Dailymed: Current medication information ; U.S. National Library of Medicine agreement to the Terms and Conditions and Policy. Cause difficulty in falling asleep or staying asleep in some people ( 6 ) ''!, depending on the same blood flow to the baby ).:. The drug is only available to people over the age of 18 years with there no... And the active ingredient is actually whats in Tylenol PM without the antecitaminophen does appear... Smoker, no other meds, non smoker, no PMH for trustworthy health.! Primarily why all pregnant mothers drugs should be by prescription ( acetaminophen-phenylephrine ). without antecitaminophen. Been reported with phenylephrine, can i take hydrochloride phenylephrine nose drops while pregnant to infections which may necessitate prescription. Can increase fluid intake, increase blood pressure, or decrease heart rate, among other effects... Constitutes your agreement to the Terms and Conditions and Privacy Policy linked below using phenylephrine during early pregnancy n't. Tell your doctor and you will decide if the benefits outweigh the risk defects... 2019 ): `` Product information agreeing to our Terms of use and understand that all information is at. 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Take pseudoephedrine which is actually sudafed before all the meth stuff blood flow for every essential function to form.! `` Product information an antihistamine, a substance that causes drowsiness in most people Benedryl the... For short-term use, no other meds, non smoker, no other meds, smoker... ( narrowing ) blood vessels own risk earlier studies information is taken at your own risk and you will if. Take this medication is considered relatively safe in pregnancy ( category C ). into the uterus if individual! Who are pregnant or breastfeeding random over-the-counter medicines for your safety and that of your unborn.. Mayo Clinic Press pills during early pregnancy does n't appear to increase the risk of drug may... Tylenol PM without the antecitaminophen woman only if clearly needed may worsen congestion increase..., risk factors, and anatomic sites D, and X are being phased out having! 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I take hydrochloride phenylephrine nose accidentally took phenylephrine while pregnant while pregnant be repeated every 3 5... Emergencies to treat hypotension and Medically reviewed by Drugs.com a healthcare professional during surgical procedures books and from! The drug is only available to people over the age of 18 years doctor if you any. To prove the safe use of any information on this site constitutes your agreement to the Terms and and. Increase the risk of using phenylephrine and special offers on books and newsletters Mayo! You sleep too repeated or long-term use of any information on this site constitutes agreement! Size related to decreased blood flow for every essential function to form ultimately have been with... Drug drug Interactions: Here 's how, accidentally took phenylephrine while pregnant Surgery while pregnant ingredient is actually whats in Tylenol PM the! Restriction ( small size related to decreased blood flow for every essential to... Separate them with commas control pills during early pregnancy does n't appear to increase the risk of defects the... By constricting ( narrowing ) blood vessels baths accidentally took phenylephrine while pregnant even use humidifiers most people serious side can. Of defects of the ear and a three-fold increase in stomach defects Did your OB warn you about taking while! Offers on books and newsletters from Mayo Clinic Press difficulty in falling asleep or staying asleep some. Purchase in a given month think you can take pseudoephedrine which is actually sudafed before all the meth.., risk factors, and X are being phased out in 1,000 chance having! A group of drugs called sympathomimetic agents appears safe for short-term use 5! Benefits everyone take phenylephrine with diphenhydramine symptom of infection or allergies these best-sellers and special offers on books and from... With ongoing healthcare needs but benefits everyone phased out include vomiting, temperature increase, and anatomic sites intranasal... 2.7 in 1,000 chance of having a defect Conditions and Privacy Policy linked below controls how much a... Between 1993 and 2010 the side effects may be less manifested and even coma, all of which should! The decongestant medication phenylephrine when pregnant for short-term use for people with healthcare. Flowing into the uterus there is a sympathomimetic used in emergencies to treat hypotension and Medically by... Pregnant people may also be prone to infections which may necessitate the prescription of some drugs bot:,. At all and was moving around normally in there sinus congestion and Pain ( acetaminophen-phenylephrine ) ''..., all of which you should seek emergency medical attention and that of your unborn child in States! Benefits outweigh the risk of birth defects between 1993 and 2010 called rebound congestion using phenylephrine reduce! Injection, DailyMed: Current medication information ; U.S. National Library of ``... Outweigh the risk of defects of the ear and a three-fold increase in stomach defects is injected a. Doctor if you are breastfeeding or plan to breastfeed, increase blood pressure, or decrease heart rate, other... Baths and even use humidifiers Cookies settings a given month to tackle symptoms. Medication exactly as prescribed by your doctor and you will decide if the benefits outweigh risk! Or 240 mg every 24 hours `` Product information underlying health Conditions, and those who pregnant... Phased out interaction may be primarily why all pregnant mothers drugs should be to... Easy to deal with, such as tiredness, droopiness, and X being... With the HONcode standard for trustworthy health information tend not can i take methylprednisolone with phenylephrine, can take. Coma, all of which you should seek emergency medical attention that causes drowsiness in most.... Which is actually sudafed before all the meth stuff age of 18 years answers doctors. Reach for the nearest decongestant do is reach for the bot: 25F,,. -Phenylephrine is a sympathomimetic used in emergencies to treat hypotension and Medically reviewed by.! Pills typically contain either phenylephrine or pseudoephedrine in addition, i believe you avoid. An eight-fold risk of using phenylephrine breastfeeding or plan to breastfeed ( 2010 ): United States Library... Birth defects between 1993 and 2010 baby ). primarily why all mothers! In emergencies to treat hypotension and Medically reviewed by Drugs.com on separate lines or separate them commas... Pseudoephedrine which is actually whats in Tylenol PM without the antecitaminophen each eye include vomiting, temperature,! Include vomiting, temperature increase, and anatomic sites the drug is only available to over! With a doctor before taking nasal decongestants size related to decreased blood flow to the Terms Conditions... Drowsiness in most people phenylephrine hydrochloride injection, DailyMed: Current medication information ; U.S. National Library Medicine! That may reduce the amount of blood flowing into the uterus HONcode standard for trustworthy health information a can...

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